Consenrich Homepage
===========================

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   :maxdepth: 1
   :caption: Contents
   :name: Consenrich Homepage
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   installation
   examples
   modules

Consenrich is an adaptive linear state estimator that yields genome-wide, uncertainty-calibrated signal tracks from noisy multi-sample HTS data.

.. image:: ../images/noise.png
  :alt: Simplified schematic of Consenrich
  :width: 85%
  :align: center

Special emphasis is placed on computational efficiency, model interpretability, and practical utility for downstream tasks that require well-resolved genome-wide signal estimates and uncertainty quantification across samples, such as:

* Consensus detection of open chromatin regions, TF footprints, nucleosome occupancy, histone modification
* Candidate selection and boundary refinement for differential analyses, fine-mapping, reporter assays, etc.

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   * - Resource
     - Link
   * - Manuscript Preprint
     - `bioRχiv <https://www.biorxiv.org/content/10.1101/2025.02.05.636702v2>`_
   * - Source Code
     - `GitHub <https://github.com/nolan-h-hamilton/Consenrich>`_
   * - Documentation, Examples, etc.
     - `(This site) <https://nolan-h-hamilton.github.io/Consenrich/>`_
   * - Contact
     - Nolan [`dοt`] Hamilton <at> unc [`dοt`] <eḏu>