ConsenrichΒΆ

Consenrich estimates regulatory signals from multi-sample functional genomics datasets.

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Input: Sequencing data (BAM files, fragments, etc.) from ATAC-seq, DNase-seq, ChIP-seq, CUT&RUN, and other functional genomics assays where multiple samples or replicates measure a shared regulatory signal but differ in local noise, artifacts, sequencing depth, assay quality, or biological heterogeneity.

Output: Consensus signal estimate tracks (bedGraph, bigWig), associated uncertainty tracks (bedGraph, bigWig), and optional consensus peak calls (narrowPeak, gappedPeak, BED).

Resource

Link

Manuscript Preprint

bioRxiv

Source Code

GitHub

Documentation, Examples, etc.

(This site)

Contact

Nolan [dot] Hamilton <at> unc [dot] edu